Protein residue surfaces are colored by mutability:
⚪ : No amino acid substitutions tolerated 🔴 : increasing tolerance for amino acid substitutions (increasing with 🔴 intensity) 🟣 : No data for residue
Ligand-protein contacts are shown as dashed lines colored by:
⬜ : Ligand contact is with amino acid side chain that has no tolerated substitutions 🟩 : Ligand contact is with peptide backbone 🟥 : Ligand contact is with amino acid side chain that has tolerated substitutions (increasing with 🔴 intensity) 🟪 : No data for contacted residue
Fitness logo plots are shown on hover of residue atoms:
Left: amino acids at this position that are consistent with virus viability. Letter heights are scaled to indicate
the fractions of the viable viral populations with the particular residue at this position Right: amino acids at this position that are present in the selected population at background frequencies,
and thus likely to be inconsistent with viral viability. Stop codons (*) can also be present in these populations
of unselected genomes